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Further Information on the Closed-Loop Artificial Pancreas Device (APD) Systems Identified
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Further Information on the Closed-Loop Artificial Pancreas Device (APD) Systems Identified

Journal: Journal of Diabetes Science and Technology

Article Title: Artificial Pancreas Device Systems for the Closed-Loop Control of Type 1 Diabetes

doi: 10.1177/1932296815617968

Figure Lengend Snippet: Further Information on the Closed-Loop Artificial Pancreas Device (APD) Systems Identified

Article Snippet: 2 , iLet (Bionic Pancreas) , USA research team: Massachusetts General Hospital and Boston University , A fully integrated and automated bihormonal closed-loop system. According to the developer’s website, clinical trials of the iLet are expected to begin in mid-2016. The system has a built-in wireless CGM that works with a Dexcom sensor and transmitter, and a dedicated handheld controller device on which its dosing algorithms run. The control algorithms “learn” about and adapt to the user’s insulin requirements, enabling personalized management. The system also contains 2 independent pumps which are automatically commanded by the insulin and glucagon dosing algorithms every 5 minutes. The bionic pancreas is being tested in the home setting. Recent published research. , Completed research: NCT02105324, NCT02092220. Ongoing or planned research: NCT02105324, NCT01833988, NCT01762059, NCT02181127, NCT02509065. Further information: http://sites.bu.edu/bionicpancreas/ .

Techniques: Control, Clinical Proteomics, Modification, Injection, Concentration Assay, Software, Battery, MicroChIP Assay, Sampling, Activity Assay